Dr. Shijie Liu's laboratory has an immediate opening for a postdoctoral research fellow. The lab aims to understand the molecular mechanisms in cardiomyocyte renewal and cardiac remodeling (including Hippo & Wnt signaling pathways) and develop gene therapy strategies to treat heart failure. In addition to standard molecular biology & biochemistry tools, the fellow will use mouse genetics, cell culture and manipulation, mass spectrometry, and the 2nd generation sequencing techniques such as single-cell RNA-seq, spatial-transcriptomics, and Cut&Run to identify gene profiles in disease models.
MAJOR DUTIES AND RESPONSIBILITIES:
Design, execute, and record laboratory experiments, and analyze the data.
Research and improve current methods and evaluate innovative techniques. Implement this knowledge in the Division/Department.
Present research at laboratory meetings, journal clubs, seminars, and meetings.
Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
Maintain currency in field through continuing education, literature, and seminars.
Attend required Cincinnati Children's training sessions and ensure regulatory compliance with all policies and procedures.
Perform other duties as assigned.
Cincinnati Children's Research and Training at a Glance
Among the top in NIH funding for pediatric research institutions
Over 1.4 million square feet of research laboratory space
900+ scientists conducting basic, translational, and clinical research
Over 2000 publications annually in top-tier journals
Access to Employee Resource Groups and Mentorship programs
Postdocs have gone on to careers in academia, biotech, pharma, teaching etc.
Ph.D. in related discipline, MD, or equivalent required.
A Ph.D. and/or M.D. degree or equivalent in a relevant research area is required. Highly motivated and creative individuals with a strong developmental biology, molecular and cell biology, and/or biochemistry background are encouraged to apply. Prior experience with mouse genetics is valuable but optional.
REQUIRED SKILLS: Excellent written, verbal, and interpersonal communication skills. Demonstrate attention to detail, strong organizational skills, supervisory ability, and an innovative approach to experimental design. Computer literate and working knowledge of software applications (word processing, spreadsheet, and database). Analytical ability sufficient to compare data; mathematical ability sufficient to perform algebraic calculations and statistical analysis. Ability to synthesize information and to create and deal with new situations by applying past experiences. Expressed willingness to teach others and share results. Capable of meeting time demands necessary to execute experiments.
Cincinnati Children's is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families (EEO/AA).
About Cincinnati Children's Hospital Medical Center
At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better, and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.